(Application Practical, Advanced and Troubleshooting)

Upon the successful completion of this course, the participants will have an understanding of principles and practices of the modern instrument’s technique XRF with different methods of calibration, standardization, and blank correction for analytical instruments.

The course creates for chemists, laboratory technicians, instrument engineers and supervisors who work in laboratory.

Day 1

• Introduction
• Analytical Chemistry Historical and review
• Basic Principle and theory of Analytical Chemistry
• Analytical Chemistry and Chemical Analysis
• Type of Chemical Analysis Methods

o Classical Methods
o Instrumental Methods

• Electromagnetic Spectrum
• Beer–Lambert Law
• Theory of Spectroscopy

o Absorption
o Emission
o Fluorescence
o Phosphorescence

Day 2

• Type of Spectroscopy Analysis

o Molecular Spectroscopy analysis
o Atomic Spectroscopy analysis
 Atomic Absorption Spectroscopy
 Atomic Emission Spectroscopy
 Atomic Fluorescence Spectroscopy

• Types of X-ray spectrometer
o X-ray Diffraction (XRD)
o X-ray Fluorescence (XRF)
• Atomic Fluorescence Spectrometer (AFS)
• XRF Instrumentation:

o Radiation Sources
o X-ray wavelength source
o Wavelength selectors
o Monochromators and filter
o Optical System
o Detector
o Computer interface

Day 3

• Sampling, Preparation and Treatment

o Liquid Samples
o Solid Samples

• Analysis Techniques
• XRF; Advantages and Disadvantages
• XRF; Maintenance & Troubleshooting

o Routine Maintenance
o Problem and troubleshot
o Safety requirement for running
o Interferences (Spectral, Chemical Ionization (
o Background Correction

• Comparing Instrumental Techniques (XRF & XRD)
• FAT Factory Acceptance Test & SAT Site Acceptance Test
• XRF; Advantages and Disadvantages

Day 4

• Chemical laboratory measurement evolution
• Analytical Method validation
• Automating Calibration, and Standardization

o Instruments Calibration and Traceability
o Reference Standard Materials
o Correction of errors and improving Blank
o Correlation Coefficient & Residual analysis in regression
o Measurement Uncertainly in testing and calibration

• Applications of XRF
o Organics and Petroleum analysis
o Petrochemical and Polymers analysis
o Environmental analysis
o Metallurgical analysis

Day 5
• The Evaluation of Results and measurements
• Type of errors in measurements
• Establishing the traceability of XRF measurements

o Principles of traceability
o Traceability: The International Definition
o International System of Quantities and Units (SI)
o Establishing Traceability
o Choice of the Reference
o Reporting Traceability

• XRF Instrumentals validation
• Characteristic of Method validation in XRF Analysis
o Specificity
o Linearity
o Range
o Accuracy & Precision
o Robustness
o Reputability, Reducibility
o Detection Limit (IDL, LOD, LOQ, LOL, ….)

• Quality Control and Quality Assurance

CDGA certificate will be issued to all attendees completing minimum of 75% of the total tuition hours of the workShop